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MYLK3 抗体 (AbBy Fluor® 750)

This anti-MYLK3 antibody (ABIN5007208) is a Rabbit Polyclonal antibody detecting MYLK3 in WB. Suitable for Human, Mouse, Rat.
产品编号 ABIN5007208
发货至: 中国

Quick Overview for MYLK3 抗体 (AbBy Fluor® 750) (ABIN5007208)

抗原

See all MYLK3 抗体
MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MYLK3 antibody is conjugated to AbBy Fluor® 750

应用范围

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Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MYLK3

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

    别名

    MYLK3

    背景

    Synonyms: caMLCK, Cardiac MyBP C associated Ca/CaM kinase, Cardiac-MyBP-C-associated Ca/CaM kinase, MLC kinase, MLCK, MLCK2, Mylk3, MYLK3_HUMAN, Myosin light chain kinase 3, Putative myosin light chain kinase 3.

    Background: The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.

    途径

    Regulation of Muscle Cell Differentiation
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