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MYLK3 抗体

MYLK3 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074736
发货至: 中国
  • 抗原 See all MYLK3 抗体
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    适用
    • 46
    • 35
    • 17
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 54
    克隆类型
    • 54
    多克隆
    标记
    • 20
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYLK3 antibody is un-conjugated
    应用范围
    • 51
    • 29
    • 24
    • 3
    • 3
    • 2
    • 2
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse MYLK3/MLCK
    Top Product
    Discover our top product MYLK3 Primary Antibody
  • 应用备注
    IHC/IF (M,R) 1:600-1:1200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    别名
    MYLK3/MLCK (MYLK3 产品)
    别名
    MLCK antibody, MLCK2 antibody, caMLCK antibody, D830007F02Rik antibody, RGD1305801 antibody, myosin light chain kinase 3 antibody, MYLK3 antibody, Mylk3 antibody
    背景
    The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
    基因ID
    213435
    NCBI登录号
    NP_001284541
    UniProt
    Q3UIZ8
    途径
    Regulation of Muscle Cell Differentiation
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