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SH3BP4 抗体 (C-Term)

This anti-SH3BP4 antibody is a 兔 多克隆 antibody detecting SH3BP4 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500704
发货至: 中国

Quick Overview for SH3BP4 抗体 (C-Term) (ABIN500704)

抗原

See all SH3BP4 抗体
SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

适用

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人, 小鼠, 大鼠

宿主

  • 16
  • 4
  • 1

克隆类型

  • 18
  • 3
多克隆

标记

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This SH3BP4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects SH3BP4.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    SH3BP4 antibody was raised against an 18 amino acid peptide from near the carboxy terminus of human SH3BP4.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

    别名

    SH3BP4

    背景

    SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.Synonyms: BOG25, EH-binding protein 10, EHB10, SH3 domain-binding protein 4, SH3BP-4, TTP, Transferrin receptor-trafficking protein

    基因ID

    23677

    NCBI登录号

    NP_055336

    UniProt

    Q9P0V3
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