RSPO1 抗体 (N-Term)
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北京 101111
Quick Overview for RSPO1 抗体 (N-Term) (ABIN500638)
抗原
See all RSPO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects RSPO1. It will not cross-react with RSPO family members.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- RSPO1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human RSPO1.
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亚型
- IgG
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anti-R-Spondin 1 (RSPO1) (AA 21-135) antibody
RSPO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-135) antibodyRSPO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 136-262) antibodyRSPO1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-263) antibodyRSPO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (N-Term) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-263) antibodyRSPO1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7A6 unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 206-240) antibodyRSPO1 适用: 人 WB 宿主: 兔 Polyclonal RB54226 unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-135) antibodyRSPO1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- RSPO1 (R-Spondin 1 (RSPO1))
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别名
- RSPO1
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背景
- RSPO1 is a member of a family of secreted growth factors that can operate through the canonical Wnt signaling pathway by stabilizing the intracellular b-catenin, thereby regulating functions mediated by b-catenin such as cell fate decisions and embryonic patterning. RSPO1 was recently identified through linkage analysis to be involved in sex determination and mammalian ovarian development. RSPO1 is thought to regulate cellular responsiveness to Wnt ligands by modulating the cell-surface expression of the Wnt co-receptor LRP6 by interfering with the DKK/Kremen-mediated internalization of LRP6 through an interaction with Kremen, resulting in increased LRP6 cell-surface levels. At least two isoforms of RSPO1 are known to exist.Synonyms: R-spondin-1, Roof plate-specific spondin-1
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基因ID
- 284654
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NCBI登录号
- NP_001033722
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UniProt
- Q2MKA7
抗原
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