RHEB 抗体 (Center)
Quick Overview for RHEB 抗体 (Center) (ABIN500597)
抗原
See all RHEB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody detects Rheb at center.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- Rheb antibody was raised against a 15 amino acid peptide from the middle region of human Rheb.
-
亚型
- IgG
-
-
anti-Ras Homolog Enriched in Brain (RHEB) (AA 1-184) antibody
RHEB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) (AA 101-184) antibodyRHEB 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) (AA 1-182) antibodyRHEB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) (AA 1-184) antibodyRHEB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) (AA 1-184) antibodyRHEB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) (Internal Region) antibodyRHEB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) (AA 1-184) antibodyRHEB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) (AA 104-134) antibodyRHEB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Enriched in Brain (RHEB) antibodyRHEB 适用: 人 ELISA, IF 宿主: 兔 Monoclonal 7G7 unconjugated Recombinant Antibody
anti-Ras Homolog Enriched in Brain (RHEB) (AA 1-184) antibodyRHEB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C11 unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 μg/mL. Immunohistochemistry on paraffin sections
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- RHEB (Ras Homolog Enriched in Brain (RHEB))
-
别名
- RHEB
-
背景
- Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure (1). While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway (2). Biochemical and genetic studies demon-strate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway (3-5). TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2 (3).Synonyms: GTP-binding protein Rheb, RHEB2, Ras homolog enriched in brain
-
基因ID
- 6009
-
UniProt
- Q15382
-
途径
- RTK signaling
抗原
-
