KAT5 抗体 (AA 51-150) (AbBy Fluor® 750)
Quick Overview for KAT5 抗体 (AA 51-150) (AbBy Fluor® 750) (ABIN5005740)
抗原
See all KAT5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KAT5 / Tip60
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亚型
- IgG
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anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 18-208) antibody
KAT5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2A11H7 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 3-512) antibodyKAT5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 1-513) antibodyKAT5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 1-230) antibodyKAT5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) antibodyKAT5 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 18-208) antibodyKAT5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4B3B4 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (C-Term) antibodyKAT5 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 山羊, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (pSer86) antibodyKAT5 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 480-530) antibodyKAT5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 230-462) antibodyKAT5 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
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别名
- KAT5 / Tip60
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背景
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Synonyms: 60 kDa Tat interactive protein, 60 kDa Tat-interactive protein, cPLA2 interacting protein, cPLA2-interacting protein, cPLA2, cPLA2 interacting protein, ESA1, Histone acetyltransferase HTATIP, Histone acetyltransferase KAT5, HIV 1 Tat interactive protein, HIV 1 Tat interactive protein, 60 kDa, HIV-1 Tat interactive protein, HTATIP, HTATIP1, Klysine acetyltransferase 5, K-acetyltransferase 5, KAT5, KAT5_HUMAN, Lysine acetyltransferase 5, PLIP, Tat interacting protein, 60 kDa, TIP, Tip60.
Background: MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
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UniProt
- Q92993
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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