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PTK7 抗体 (N-Term)

This anti-PTK7 antibody is a 兔 多克隆 antibody detecting PTK7 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500555
发货至: 中国

Quick Overview for PTK7 抗体 (N-Term) (ABIN500555)

抗原

See all PTK7 抗体
PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

适用

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人, 小鼠, 大鼠

宿主

  • 50
  • 10
  • 2
  • 1
  • 1

克隆类型

  • 53
  • 11
多克隆

标记

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This PTK7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects PTK7 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    PTK7 antibody was raised against a 15 amino acid peptide from near the amino terminus of human PTK7.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

    别名

    PTK7 / CCK4

    背景

    Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.Synonyms: CCK-4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7

    基因ID

    5754

    NCBI登录号

    NP_002812

    UniProt

    Q13308

    途径

    RTK signaling, Tube Formation
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