POFUT1 抗体 (N-Term)
(1 reference)Quick Overview for POFUT1 抗体 (N-Term) (ABIN500521)
抗原
See all POFUT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects POFUT1. It is predicted to not cross-react with POFUT2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Peptide affinity chromatography
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免疫原
- POFUT1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human POFUT1.
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亚型
- IgG
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anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 238-388) antibody
POFUT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 1-194) antibodyPOFUT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 243-393) antibodyPOFUT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) antibodyPOFUT1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 85-194) antibodyPOFUT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (C-Term) antibodyPOFUT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (C-Term) antibodyPOFUT1 适用: 人, 犬, 猴, Pig WB, IHC, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 101-150) antibodyPOFUT1 适用: 人, 小鼠, 大鼠, 犬, 猴, Pig, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 344-373), (C-Term) antibodyPOFUT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32435 unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (Middle Region) antibodyPOFUT1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: .5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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: "Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features." in: Glycobiology, Vol. 28, Issue 5, pp. 276-283, (2018) (PubMed).
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: "Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features." in: Glycobiology, Vol. 28, Issue 5, pp. 276-283, (2018) (PubMed).
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- POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))
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别名
- POFUT1
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背景
- POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch, mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling. At least two isoforms of POFUT1 are known to exist.Synonyms: FUT12, GDP-fucose protein O-fucosyltransferase 1, KIAA0180, O-FucT-1, Peptide-O-fucosyltransferase 1
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基因ID
- 23509
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NCBI登录号
- NP_056167
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UniProt
- Q9H488
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途径
- Notch Signaling, SARS-CoV-2 Protein Interactome
抗原
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