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ICOS 抗体 (AA 51-150) (AbBy Fluor® 680)

This anti-ICOS antibody is a 兔 多克隆 antibody detecting ICOS in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN5005030
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ICOS 抗体 (AA 51-150) (AbBy Fluor® 680) (ABIN5005030)

抗原

See all ICOS 抗体
ICOS (Inducible T-Cell Co-Stimulator (ICOS))

适用

  • 106
  • 40
  • 34
  • 5

宿主

  • 87
  • 17
  • 12
  • 4
  • 2
  • 1

克隆类型

  • 71
  • 51
  • 1
多克隆

标记

  • 53
  • 16
  • 8
  • 8
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This ICOS antibody is conjugated to AbBy Fluor® 680

应用范围

  • 72
  • 37
  • 35
  • 32
  • 21
  • 16
  • 12
  • 12
  • 10
  • 9
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    特异性

    This antibody may also have a secondary cross-reactivity with AP-1 complex-associated regulatory protein due to a 77 % non-contiguous sequence similarity in the corresponding immunogen region.

    交叉反应

    预测反应

    Mouse,Rat,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ICOS

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ICOS (Inducible T-Cell Co-Stimulator (ICOS))

    别名

    ICOS/CD278

    背景

    Synonyms: AILIM, CD278, CVID1, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, ICOS

    Background: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

    基因ID

    29851

    UniProt

    Q9Y6W8

    途径

    Cancer Immune Checkpoints
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