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PICALM 抗体 (N-Term)

PICALM 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500493
发货至: 中国
  • 抗原 See all PICALM 抗体
    PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 23
    • 23
    • 22
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    • 2
    克隆类型
    • 37
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PICALM antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    PICALM antibody was raised against a 15 amino acid peptide from near the amino terminus of human PICALM.
    亚型
    IgG
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  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
    别名
    PICALM (PICALM 产品)
    别名
    LAP-3 antibody, PEPS antibody, CALM antibody, CLTH antibody, LAP antibody, PAP180 antibody, fit-1 antibody, fit1 antibody, mKIAA4114 antibody, Calm antibody, leucine aminopeptidase 3 antibody, phosphatidylinositol binding clathrin assembly protein antibody, si:ch211-200p22.4 antibody, LAP3 antibody, PICALM antibody, Picalm antibody, si:ch211-200p22.4 antibody
    背景
    PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).Synonyms: CALM, Clathrin assembly lymphoid myeloid leukemia protein, Phosphatidylinositol-binding clathrin assembly protein
    基因ID
    8301
    NCBI登录号
    NP_009097
    UniProt
    Q13492
    途径
    Synaptic Membrane
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