PICALM 抗体 (N-Term)
Quick Overview for PICALM 抗体 (N-Term) (ABIN500493)
抗原
See all PICALM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- PICALM antibody was raised against a 15 amino acid peptide from near the amino terminus of human PICALM.
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亚型
- IgG
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anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 517-624) antibody
PICALM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 420-646) antibodyPICALM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 251-350) antibodyPICALM 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 385-415) antibodyPICALM 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB53756 unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 512-543) antibodyPICALM 适用: 人 WB 宿主: 兔 Polyclonal RB54131 unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 1-307) antibodyPICALM 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 1-610) antibodyPICALM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 438-487) antibodyPICALM 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 277-326) antibodyPICALM 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 290-460) antibodyPICALM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
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别名
- PICALM
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背景
- PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).Synonyms: CALM, Clathrin assembly lymphoid myeloid leukemia protein, Phosphatidylinositol-binding clathrin assembly protein
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基因ID
- 8301
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NCBI登录号
- NP_009097
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UniProt
- Q13492
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途径
- Synaptic Membrane
抗原
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