HTRA2 抗体 (C-Term)
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Quick Overview for HTRA2 抗体 (C-Term) (ABIN500413)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects HTRA2 / PRSS25.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Ion exchange chromatography
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免疫原
- OMI antibody was raised against a peptide corresponding to 15 amino acids near the C- terminus of human OMI.
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亚型
- IgG
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anti-HtrA Serine Peptidase 2 (HTRA2) (AA 278-458) antibody
HTRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6H7A8 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 334-458) antibodyHTRA2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 359-458) antibodyHTRA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (C-Term) antibodyHTRA2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人 WB, IHC (p), IP 宿主: 小鼠 Monoclonal 18-01-83 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 231-330) antibodyHTRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6110 unconjugated Recombinant Antibody
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 8G11-4B8-4F10-G5 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (C-Term) antibodyHTRA2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 335-350) antibodyHTRA2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 196C429 unconjugated
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应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- HTRA2 / PRSS25
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背景
- Inhibitor of apoptosis proteins (IAPs) were initially identified in baculoviruses as proteins that inhibit apoptosis of the host cells to allow time for viral replication (1). Cellular homologues containing at least one baculoviral IAP repeat (BIR) motif essential for their anti-apoptosis activity have been identified in yeasts and higher organisms and often act by binding and inhibiting processed caspases (reviewed in 2). The activity of these proteins can be modulated by the expression of proteins such as Smac/DIABLO and XAF-1 which displace or prevent the binding of caspases by IAPs (reviewed in 3). Recently, a mitochondrial serine protease termed Omi/HtrA2 has been found to bind IAPs (4). Similar to Smac, Omi possesses a conserved IAP-binding motif, but acts to cleave IAPs to irreversibly inactivate IAPs and promote apoptosis (5).Synonyms: High temperature requirement protein A2, OMI, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, mitochondrial Serine protease HTRA2
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基因ID
- 27429
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UniProt
- O43464
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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