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Occludin 抗体 (C-Term)

This anti-Occludin antibody is a 兔 多克隆 antibody detecting Occludin in WB, IF, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN500409
发货至: 中国

Quick Overview for Occludin 抗体 (C-Term) (ABIN500409)

抗原

See all Occludin (OCLN) 抗体
Occludin (OCLN)

适用

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人, 小鼠, 大鼠

宿主

  • 95
  • 19
  • 3
  • 1

克隆类型

  • 89
  • 29
多克隆

标记

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This Occludin antibody is un-conjugated

应用范围

  • 95
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  • 27
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  • 2
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
    • 16
    • 10
    • 9
    • 6
    • 6
    • 3
    • 3
    • 3
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    • 2
    • 2
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detectc OCLN.

    纯化方法

    Peptide affinity chromatography

    免疫原

    OCLN antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human OCLN.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Liang, Zhang, Deng, He, Liang, Liang, Chen, Tang, Chen, Yang: "The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 5378961, (2018) (PubMed).

    Zhang, Tang, Deng, Chen, Liang, Xie, He, Chen, Yang: "Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats." in: Biomedicine & pharmacotherapy, Vol. 102, pp. 1025-1036, (2018) (PubMed).

  • 抗原

    Occludin (OCLN)

    别名

    Occludin

    背景

    Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.Synonyms: OCLN

    基因ID

    4950

    UniProt

    Q16625

    途径

    Cell-Cell Junction Organization, Hepatitis C
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