Occludin 抗体 (C-Term)
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Quick Overview for Occludin 抗体 (C-Term) (ABIN500409)
抗原
See all Occludin (OCLN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detectc OCLN.
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纯化方法
- Peptide affinity chromatography
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免疫原
- OCLN antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human OCLN.
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亚型
- IgG
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anti-Occludin (OCLN) (AA 431-522) antibody
OCLN 适用: 人, 小鼠, Pig WB, ELISA, FACS, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (C-Term) antibodyOCLN 适用: 人 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 423-522) antibodyOCLN 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Occludin (OCLN) (AA 1-522) antibodyOCLN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 1-522) antibodyOCLN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 282-415) antibodyOCLN 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal OCLN-2181 unconjugated
anti-Occludin (OCLN) (AA 350-450) antibodyOCLN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 285-430) antibodyOCLN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 282-415) antibodyOCLN 适用: 人 IHC 宿主: 小鼠 Monoclonal 415M unconjugated
anti-Occludin (OCLN) (C-Term) antibodyOCLN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal OC-3F10 unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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: "Angulin-1/LSR inhibition transiently disrupts the blood-tumor barrier to enhance doxil permeability and impair malignant glioma progression." in: bioRxiv : the preprint server for biology, (2025) (PubMed).
: "The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 5378961, (2018) (PubMed).
: "Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats." in: Biomedicine & pharmacotherapy, Vol. 102, pp. 1025-1036, (2018) (PubMed).
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: "Angulin-1/LSR inhibition transiently disrupts the blood-tumor barrier to enhance doxil permeability and impair malignant glioma progression." in: bioRxiv : the preprint server for biology, (2025) (PubMed).
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- Occludin (OCLN)
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别名
- Occludin
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背景
- Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.Synonyms: OCLN
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基因ID
- 4950
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UniProt
- Q16625
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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