Neurturin 抗体 (AA 178-193)
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Quick Overview for Neurturin 抗体 (AA 178-193) (ABIN500336)
抗原
See all Neurturin (NRTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 178-193
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特异性
- This antibody detects Neurturin.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- Neurturin antibody was raised against a peptide corresponding to amino acids 178 to 193 of human neurturin.
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亚型
- IgG
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anti-Neurturin (NRTN) (AA 151-197) antibody
NRTN 适用: 人, 小鼠, 犬, 小鸡 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neurturin (NRTN) antibodyNRTN 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurturin (NRTN) (C-Term) antibodyVerified NRTN 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Neurturin (NRTN) (C-Term) antibodyVerified NRTN 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neurturin (NRTN) (AA 178-193) antibodyNRTN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurturin (NRTN) antibodyNRTN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D12 unconjugated
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应用备注
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Neurturin (NRTN)
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别名
- Neurturin
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背景
- Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently (3-8) and termed GDNFRb, Ret ligand 2 (RETL2) or TGF-Β-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently. NTN binds to and forms a complex with GFRalpha-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.Synonyms: NRTN
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基因ID
- 4902
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NCBI登录号
- NP_004549
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UniProt
- Q99748
抗原
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