NANOS3 抗体 (C-Term)
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Quick Overview for NANOS3 抗体 (C-Term) (ABIN500324)
抗原
See all NANOS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Nanos3 at C-term. It will not cross-react with either Nanos 1 or Nanos2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- Nanos3 antibody was raised against a 16 amino acid peptide near the carboxy terminus of the human Nanos3.
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亚型
- IgG
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anti-Nanos Homolog 3 (NANOS3) (AA 1-100) antibody
NANOS3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-Nanos Homolog 3 (NANOS3) (AA 21-192) antibodyNANOS3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nanos Homolog 3 (NANOS3) (AA 101-173) antibodyNANOS3 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- NANOS3 (Nanos Homolog 3 (NANOS3))
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别名
- NANOS3
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背景
- Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.Synonyms: MGC120114, NANOS1L, NOS3, Nanos homolog 3
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基因ID
- 342977
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NCBI登录号
- NP_001092092
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UniProt
- Q495E5
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途径
- ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
抗原
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