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NAIP 抗体 (C-Term)

This anti-NAIP antibody is a 兔 多克隆 antibody detecting NAIP in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN500306
发货至: 中国

Quick Overview for NAIP 抗体 (C-Term) (ABIN500306)

抗原

See all NAIP 抗体
NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

适用

  • 44
  • 5
  • 2

宿主

  • 44
  • 2
  • 1

克隆类型

  • 41
  • 6
多克隆

标记

  • 24
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NAIP antibody is un-conjugated

应用范围

  • 33
  • 17
  • 15
  • 13
  • 13
  • 8
  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects NAIP at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Peptide affinity chromatography

    免疫原

    NAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 to 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

    别名

    NAIP

    背景

    Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy (1,2). Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR), these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO (4), suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported (5).Synonyms: BIRC1, Baculoviral IAP repeat-containing protein 1

    基因ID

    4671

    UniProt

    Q13075

    途径

    Apoptosis, Inflammasome
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