Mre11 抗体 (N-Term)
Quick Overview for Mre11 抗体 (N-Term) (ABIN500290)
抗原
See all Mre11 (MRE11A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- At least two isoforms of MRE11 are known to exist, this antibody will recognize both isoforms.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Peptide Affinity Chromatography
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免疫原
- 14 amino acid peptide from near the amino terminus Human MRE11
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亚型
- IgG
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anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibody
MRE11A 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) antibodyMRE11A 适用: 人, 大鼠, 小鼠, 小鸡, Hamster WB, IHC, IP, IF, ICC, FACS, ChIP 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 451-550) antibodyMRE11A 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibodyMRE11A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 375-609) antibodyMRE11A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibodyMRE11A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (C-Term) antibodyMRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Internal Region) antibodyMRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 2-239) antibodyMRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-206) antibodyMRE11A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H4-F4 unconjugated
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应用备注
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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别名
- MRE11
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背景
- MRE11 is involved in the repair of DNA double strand breaks as part of a complex that includes the Rad50 and NBS1 protein and is thought to act in the same pathway as the A-T mutated (ATM) protein. By itself, the protein has 3\' to 5\' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for non-homologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. Mutations in this protein result in a novel ataxia telangiectasia-like disorder (ATLD). Unlike the ATM protein, MRE11 is necessary proper mammalian development.Synonyms: Double-strand break repair protein MRE11A, HNGS1, MRE11 homolog 1, MRE11 meiotic recombination 11 homolog A, MRE11A
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基因ID
- 4361
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UniProt
- P49959
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途径
- DNA Damage Repair
抗原
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