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FOXO3 抗体 (pSer253) (AbBy Fluor® 680)

This anti-FOXO3 antibody is a 兔 多克隆 antibody detecting FOXO3 in WB, IF (cc), FACS 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5002859
发货至: 中国

Quick Overview for FOXO3 抗体 (pSer253) (AbBy Fluor® 680) (ABIN5002859)

抗原

See all FOXO3 抗体
FOXO3 (Forkhead Box O3 (FOXO3))

适用

  • 124
  • 80
  • 71
  • 9
  • 7
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 125
  • 6
  • 1
  • 1

克隆类型

  • 110
  • 23
多克隆

标记

  • 80
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXO3 antibody is conjugated to AbBy Fluor® 680

应用范围

  • 97
  • 55
  • 52
  • 34
  • 22
  • 22
  • 21
  • 14
  • 14
  • 13
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 37
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer253

    特异性

    This phosphorylation site is homologous to Ser252 in Mouse and Rat.

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FOXO3 (Forkhead Box O3 (FOXO3))

    别名

    FoxO3a

    背景

    Synonyms: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3

    Background: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

    基因ID

    2309

    UniProt

    O43524

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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