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MED4 抗体 (C-Term)

This anti-MED4 antibody is a 兔 多克隆 antibody detecting MED4 in WB, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN500270
发货至: 中国

Quick Overview for MED4 抗体 (C-Term) (ABIN500270)

抗原

See all MED4 抗体
MED4 (Mediator Complex Subunit 4 (MED4))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MED4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    • 1
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    • 1
    • 1
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    C-Term

    特异性

    This antibody detects MED4. It only recognizes the largest isoform.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    MED4 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MED4.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MED4 (Mediator Complex Subunit 4 (MED4))

    别名

    MED4

    背景

    The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment. At least three isoforms of MED4 are known to exist.Synonyms: ARC36, Activator-recruited cofactor 36 kDa component, DRIP36, HSPC126, Mediator complex 4, Mediator of RNA polymerase II transcription subunit 4, TRAP/SMCC/PC2 subunit p36 subunit, VDRIP, Vitamin D3 receptor-interacting protein complex 36 kDa component

    基因ID

    29079

    NCBI登录号

    NP_054885

    UniProt

    Q9NPJ6

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
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