MC4R 抗体 (N-Term)
Quick Overview for MC4R 抗体 (N-Term) (ABIN500250)
抗原
See all MC4R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects MC4-R.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- MC4R antibody was raised against a 19 amino acid peptide near the amino terminus of human MC4R.
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亚型
- IgG
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anti-Melanocortin 4 Receptor (MC4R) (AA 1-50) antibody
MC4R 适用: 人, 大鼠, 小鼠 ELISA, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (N-Term) antibodyMC4R 适用: 人, 猴, 马 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 6-20), (Extracellular) antibodyMC4R 适用: 人 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 25-57) antibodyMC4R 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52063 unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 21-33) antibodyMC4R 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (Cytoplasmic Domain) antibodyMC4R 适用: 人, 绵羊, 兔, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (C-Term) antibodyMC4R 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (C-Term) antibodyMC4R 适用: 人, 大鼠, 小鼠, 绵羊, 兔, Cow, 猴, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 1-50) antibody (AbBy Fluor® 488)MC4R 适用: 人, 大鼠, 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-Melanocortin 4 Receptor (MC4R) (N-Term) antibodyRecent MC4R 适用: 人 ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- MC4R (Melanocortin 4 Receptor (MC4R))
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别名
- MC4-R
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背景
- The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways. It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity, activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling. MC4R-null mice display maturity onset obesity characterized by hyperphagia, increased adiposity, hyperinsulinaemia and hyperleptinaemia, suggesting that like other obesity-linked genes such as FTO, PTER, and NPC1, MC4R is a potential candidate target for the treatment of obesity.Synonyms: MC4R, Melanocortin receptor 4
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基因ID
- 4160
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NCBI登录号
- NP_005903
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UniProt
- P32245
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途径
- Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
抗原
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