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Ephrin B1 抗体 (pTyr324, pTyr329) (AbBy Fluor® 680)

This AbBy Fluor® 680-conjugated 兔 多克隆 anti-Ephrin B1 antibody specifically detects Ephrin B1 in WB, IF (p) 和 IF (cc). The antibody is reactive with 人 samples.
产品编号 ABIN5002046
发货至: 中国
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Quick Overview for Ephrin B1 抗体 (pTyr324, pTyr329) (AbBy Fluor® 680) (ABIN5002046)

抗原

See all Ephrin B1 (EFNB1) 抗体
Ephrin B1 (EFNB1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Ephrin B1 antibody is conjugated to AbBy Fluor® 680

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
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    pTyr324, pTyr329

    特异性

    These phosphorylation sites are homologous to Tyr323 + Tyr328 in Mouse.

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr324/329

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Ephrin B1 (EFNB1)

    别名

    EFNB1

    背景

    Synonyms: CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2, Ephrin-B1, EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EFNB1

    Background: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

    基因ID

    1947

    UniProt

    P98172

    途径

    RTK signaling
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