LIN28A 抗体 (C-Term)
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Quick Overview for LIN28A 抗体 (C-Term) (ABIN500176)
抗原
See all LIN28A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- Lin28 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Lin28.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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别名
- LIN28
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背景
- Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.Synonyms: CSDD1, LIN-28, LIN28A, Lin-28 homolog A, ZCCHC1
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基因ID
- 79727
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UniProt
- Q9H9Z2
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途径
- Stem Cell Maintenance
抗原
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