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DHX58 抗体 (C-Term)

This anti-DHX58 antibody is a 兔 多克隆 antibody detecting DHX58 in WB 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN500164
发货至: 中国

Quick Overview for DHX58 抗体 (C-Term) (ABIN500164)

抗原

See all DHX58 抗体
DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

适用

  • 38
  • 8
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 25
  • 12
  • 1

克隆类型

  • 28
  • 10
多克隆

标记

  • 26
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DHX58 antibody is un-conjugated

应用范围

  • 29
  • 20
  • 16
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects DHX58 at C-term.

    纯化方法

    Peptide affinity chromatography

    免疫原

    LGP2 antibody was raised against a 12 amino acid peptide from near the carboxy terminus of human LGP2.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

    别名

    DHX58

    背景

    Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.Synonyms: ATP-dependent RNA helicase DHX58, ATP-dependent helicase LGP2, D11LGP2E, DHX58, LGP2, Protein D11Lgp2 homolog

    基因ID

    79132

    UniProt

    Q96C10
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