DZIP1 抗体 (AA 21-120) (AbBy Fluor® 680)
Quick Overview for DZIP1 抗体 (AA 21-120) (AbBy Fluor® 680) (ABIN5001611)
抗原
See all DZIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DZIP1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DZIP1 (DAZ Interacting Protein 1 (DZIP1))
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别名
- DZIP1
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背景
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Synonyms: DAZ interacting protein 1/2, DAZ interacting protein testis1, DZIP, DZIP2, DZIPt1, Zinc finger DAZ interacting protein 1, Zinc finger protein DZIP1, Zinc finger protein DZIPt1.
Background: DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility.
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途径
- Hedgehog Signaling, Protein targeting to Nucleus
抗原
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