DOK7 抗体 (AA 21-120) (AbBy Fluor® 750)
Quick Overview for DOK7 抗体 (AA 21-120) (AbBy Fluor® 750) (ABIN5001453)
抗原
See all DOK7 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 21-120
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                                            交叉反应
- 大鼠
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                                            预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from human DOK7
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                                            亚型
- IgG
 
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                                            应用备注
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                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - DOK7 (Docking Protein 7 (DOK7))
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                                            别名
- DOK7
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                                            背景
- 
                        Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7. Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness. 
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                                            途径
- Skeletal Muscle Fiber Development
 抗原
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