DNASE1 抗体 (AA 101-200) (AbBy Fluor® 750)
Quick Overview for DNASE1 抗体 (AA 101-200) (AbBy Fluor® 750) (ABIN5001395)
抗原
See all DNASE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DNase I
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亚型
- IgG
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anti-Deoxyribonuclease I (DNASE1) (AA 19-259) antibody
DNASE1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 22-282) antibodyDNASE1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) antibodyDNASE1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 1-252) antibodyDNASE1 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 19-259) antibodyDNASE1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 2-1# unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 78-231) antibodyDNASE1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 87-121) antibodyDNASE1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB49355 unconjugated
anti-Deoxyribonuclease I (DNASE1) antibodyDNASE1 适用: 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (N-Term) antibodyDNASE1 适用: 人, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 19-259) antibodyDNASE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 7# unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DNASE1 (Deoxyribonuclease I (DNASE1))
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别名
- DNase 1
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背景
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Synonyms: RNASE1, Dornase alfa, Deoxyribonuclease 1, Deoxyribonuclease I, Deoxyribonuclease1, DeoxyribonucleaseI, DNASE 1, DNase I lysosomal, DNASE1, DNaseI, DNL 1, DNL1, DRNI, Human urine deoxyribonuclease I, DNAS1_HUMAN.
Background: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA, it was the first DNase to be crystallized, and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.
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基因ID
- 1773
抗原
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