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CD82 抗体 (C-Term)

CD82 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500108
发货至: 中国
  • 抗原 See all CD82 抗体
    CD82
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 57
    • 36
    • 5
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 26
    克隆类型
    • 52
    • 27
    多克隆
    标记
    • 29
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD82 antibody is un-conjugated
    应用范围
    • 51
    • 32
    • 22
    • 20
    • 18
    • 18
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects CD82 at C-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    KAI1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human KAI1.
    亚型
    IgG
    Top Product
    Discover our top product CD82 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD82
    别名
    CD82 (CD82 产品)
    别名
    AA682076 antibody, AL023070 antibody, C33 antibody, IA4 antibody, Kai1 antibody, Tspan27 antibody, 4F9 antibody, GR15 antibody, KAI1 antibody, R2 antibody, SAR2 antibody, ST6 antibody, TSPAN27 antibody, CD82 antigen antibody, CD82 molecule antibody, Cd82 molecule antibody, Cd82 antibody, CD82 antibody
    背景
    KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least two isoforms of KAI1 are known to exist.Synonyms: C33 antigen, IA4, Inducible membrane protein R2, KAI1, Kangai-1, Metastasis suppressor Kangai-1, SAR2, ST6, Suppressor of tumorigenicity protein 6, TSPAN27, Tetraspanin-27
    基因ID
    3732
    NCBI登录号
    NP_002222
    UniProt
    P27701
    途径
    p53 Pathway
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