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DAXX 抗体 (pSer517) (AbBy Fluor® 750)

This anti-DAXX antibody is a 兔 多克隆 antibody detecting DAXX in WB, IF (p), IF (cc) 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN5001033
发货至: 中国

Quick Overview for DAXX 抗体 (pSer517) (AbBy Fluor® 750) (ABIN5001033)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

  • 159
  • 61
  • 50
  • 7
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
人, 大鼠, 小鼠

宿主

  • 142
  • 18

克隆类型

  • 131
  • 29
多克隆

标记

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  • 7
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  • 3
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  • 1
This DAXX antibody is conjugated to AbBy Fluor® 750

应用范围

  • 131
  • 64
  • 64
  • 38
  • 36
  • 25
  • 21
  • 20
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  • 15
  • 7
  • 3
  • 3
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  • 1
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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
  • 抗原表位

    • 23
    • 21
    • 16
    • 15
    • 15
    • 9
    • 5
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer517

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human DAXX around the phosphorylation site of Ser517

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    Synonyms: BING 2, BING2, DAP 6, DAP6, Death associated protein 6, Death domain associated protein 6, EAP 1, EAP1, ETS1 associated protein 1, Fas death domain associated protein, hDaxx, MGC126245, MGC126246, DAXX_HUMAN.

    Background: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways.

    基因ID

    1616

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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