KDM4A 抗体 (Center)
Quick Overview for KDM4A 抗体 (Center) (ABIN500080)
抗原
See all KDM4A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody detects JMJD2A.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- JMJD2A antibody was raised against a 14 amino acid peptide from near the center of human JMJD2A.
-
亚型
- IgG
-
-
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 141-310) antibody
KDM4A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 932-1057) antibodyKDM4A 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E10G4 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 585-815) antibodyKDM4A 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5H1 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 127-364) antibodyKDM4A 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 DB, ICC 宿主: 小鼠 Monoclonal 3559D5a unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
-
别名
- JMJD2A / KDM4A
-
背景
- Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. The first member of this group, JMJD2A, is widely expressed in human tissues and cell lines and functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. JMJD2A can also form a complex with the androgen receptor (AR), a transcription factor that is pivotal for the development of prostate cancer. Overexpression of JMJD2A stimulates AR function and this stimulation is dependent on JMJD2A catalytic activity, suggesting that JMJD2A might be a critical protein with roles in cell proliferation and oncogenesis.Synonyms: JHDM3A, JMJD2, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, KIAA0677, Lysine-specific demethylase 4A
-
基因ID
- 9682
-
UniProt
- O75164
-
途径
- Warburg Effect
抗原
-
