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KDM3A 抗体 (N-Term)

This anti-KDM3A antibody is a 兔 多克隆 antibody detecting KDM3A in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500074
发货至: 中国

Quick Overview for KDM3A 抗体 (N-Term) (ABIN500074)

抗原

See all KDM3A 抗体
KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This KDM3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects KDM3A / JHDM2A. It will not cross-react with JMJD1B or JMJD1C.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    JMJD1A antibody was raised against a 16 amino acid peptide from near the amino terminus of human JMJD1A.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

    别名

    KDM3A / JHDM2A

    背景

    The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.Synonyms: JMJD1, JMJD1A, JmjC domain-containing histone demethylation protein 2A, Jumonji domain-containing protein 1A, KIAA0742, Lysine-specific demethylase 3A, TSGA

    基因ID

    55818

    NCBI登录号

    NP_060903

    UniProt

    Q9Y4C1

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect
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