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Cullin 2 抗体 (AA 365-745) (AbBy Fluor® 750)

This AbBy Fluor® 750-conjugated 兔 多克隆 anti-Cullin 2 antibody specifically detects Cullin 2 in IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN5000712
发货至: 中国
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Quick Overview for Cullin 2 抗体 (AA 365-745) (AbBy Fluor® 750) (ABIN5000712)

抗原

See all Cullin 2 (CUL2) 抗体
Cullin 2 (CUL2)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cullin 2 antibody is conjugated to AbBy Fluor® 750

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 365-745

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Cullin 2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Cullin 2 (CUL2)

    别名

    Cullin 2

    背景

    Synonyms: Cullin2, Cullin-2, CUL 2, MGC131970, CUL2_HUMAN.

    Background: Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

    基因ID

    8453

    途径

    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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