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IRF3 抗体 (Intermediate Domain)

IRF3 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500056
发货至: 中国
  • 抗原 See all IRF3 抗体
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    抗原表位
    • 17
    • 15
    • 15
    • 14
    • 13
    • 9
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    Intermediate Domain
    适用
    • 139
    • 91
    • 56
    • 31
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    宿主
    • 150
    • 12
    • 2
    克隆类型
    • 135
    • 29
    多克隆
    标记
    • 85
    • 12
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
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    This IRF3 antibody is un-conjugated
    应用范围
    • 118
    • 67
    • 32
    • 29
    • 28
    • 27
    • 19
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
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    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    IRF3 antibody antibody was raised against a peptide corresponding to 14 amino acids near the center of human IRF3.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human IRF3 (Intermediate Domain) Peptide
    亚型
    IgG
    Top Product
    Discover our top product IRF3 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    别名
    IRF3 (IRF3 产品)
    别名
    irf3 antibody, IRF3 antibody, C920001K05Rik antibody, IRF-3 antibody, interferon regulatory factor 3 antibody, interferon regulatory factor 7 antibody, irf3 antibody, IRF3 antibody, irf-3 antibody, Irf3 antibody, IRF7 antibody
    背景
    Interferons (IFN)s are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms (1 for review). During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF3 is present in an inactive form in the cytoplasm of most cells (2). Following viral infection, IRF3 can be activated by IkappaB kinase-epsilon and TANK-binding kinase 1 (TBK1) (3,4), whereupon IRF3 translocates to the nucleus. IRF3 can also be activated by stimulation of toll-like receptor 3 (TLR3) by dsRNA (3,5). IRF3 exists as at least two distinct isoforms.Synonyms: IRF-3, Interferon regulatory factor 3
    基因ID
    3661
    NCBI登录号
    NP_001562
    UniProt
    Q14653
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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