IRAK2 抗体 (C-Term)
Quick Overview for IRAK2 抗体 (C-Term) (ABIN500038)
抗原
See all IRAK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- IRAK2 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy-terminus of mouse IRAK2a which is common to all four isoforms. mIRAK2 antibody will also recognize human IRAK2. Anti-IRAK2 has no cross response to IRAK. Anti-IRAK2 will also recognize human IRAK2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human IRAK2 (C-Terminus) Peptide
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亚型
- IgG
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anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) antibody
IRAK2 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 111-210) antibodyIRAK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6C7 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (C-Term) antibodyIRAK2 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 211-458) antibodyIRAK2 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 1-270) antibodyIRAK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 1-270) antibodyIRAK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) antibodyIRAK2 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 600-616), (C-Term) antibodyIRAK2 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 235-521) antibodyIRAK2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 549-581) antibodyIRAK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 0.5 - 1 μg/mL. A 65 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
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别名
- IRAK2
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背景
- The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappaB, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family has been identified and designated IRAK2 (1). Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappaB activation. IRAKs also associate with Toll like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF-?B activation (2,3). Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory response. Unlike human IRAK2, murine IRAK2 exists as four alternately spliced isoforms (IRAK2a-d), with two isoforms (IRAK2c and d) acting in an inhibitory fashion (4). IRAK2 is expressed in a variety of tissues.Synonyms: IRAK-2, Interleukin-1 receptor-associated kinase-like 2
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基因ID
- 108960
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UniProt
- Q8CFA1
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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