IL-34 抗体 (N-Term)
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北京 101111
Quick Overview for IL-34 抗体 (N-Term) (ABIN500016)
抗原
See all IL-34 (IL34) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to IL-34.
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交叉反应 (详细)
- Species reactivity (tested):Human brain tissue.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- IL-34 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-34.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 0.25 - 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- IL-34 (IL34) (Interleukin 34 (IL34))
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别名
- Interleukin-34 / IL34
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背景
- Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.Synonyms: C16orf77, IL-34
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基因ID
- 146433
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UniProt
- Q6ZMJ4
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途径
- RTK signaling
抗原
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