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IL-34 抗体 (N-Term)

This anti-IL-34 antibody is a 兔 多克隆 antibody detecting IL-34 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500016
发货至: 中国

Quick Overview for IL-34 抗体 (N-Term) (ABIN500016)

抗原

See all IL-34 (IL34) 抗体
IL-34 (IL34) (Interleukin 34 (IL34))

适用

  • 44
  • 31
  • 8
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 54
  • 17
  • 4
  • 1

克隆类型

  • 58
  • 18
多克隆

标记

  • 42
  • 10
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-34 antibody is un-conjugated

应用范围

  • 58
  • 31
  • 29
  • 20
  • 16
  • 13
  • 13
  • 8
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody reacts to IL-34.

    交叉反应 (详细)

    Species reactivity (tested):Human brain tissue.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    IL-34 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-34.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 0.25 - 0.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    IL-34 (IL34) (Interleukin 34 (IL34))

    别名

    Interleukin-34 / IL34

    背景

    Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.Synonyms: C16orf77, IL-34

    基因ID

    146433

    UniProt

    Q6ZMJ4

    途径

    RTK signaling
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