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IL23A 抗体 (N-Term)

This anti-IL23A antibody is a 兔 多克隆 antibody detecting IL23A in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499998
发货至: 中国
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Quick Overview for IL23A 抗体 (N-Term) (ABIN499998)

抗原

See all IL23A 抗体
IL23A (Interleukin 23, alpha subunit p19 (IL23A))

适用

  • 53
  • 23
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  • 1
人, 小鼠

宿主

  • 39
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  • 11
  • 2
  • 1

克隆类型

  • 41
  • 25
多克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL23A antibody is un-conjugated

应用范围

  • 35
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  • 1
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  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 7
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody reacts to Il-23.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    IL-23 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-23.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    IL23A (Interleukin 23, alpha subunit p19 (IL23A))

    别名

    Interleukin-23 alpha / IL23A

    背景

    Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF

    基因ID

    51561

    UniProt

    Q9NPF7

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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