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IL-21 抗体 (Intermediate Domain)

The 兔 多克隆 anti-IL-21 antibody (ABIN499986) specifically detects IL-21 in WB, IF 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN499986
发货至: 中国
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Quick Overview for IL-21 抗体 (Intermediate Domain) (ABIN499986)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-21 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Intermediate Domain

    特异性

    IL-21 antibody was raised against a synthetic peptide corresponding to 15 amino acids near the center of human IL-21 precursor.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human IL-21 (Intermediate Domain) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 18 kDa band can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    Interleukin-21 / IL21

    背景

    A novel cytokine was recently identified in human and mouse and designated IL-21 , which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.Synonyms: IL-21, Za11

    基因ID

    59067

    NCBI登录号

    NP_068575

    UniProt

    Q9HBE4

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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