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INSM1 抗体 (N-Term)

INSM1 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499952
发货至: 中国
  • 抗原 See all INSM1 抗体
    INSM1 (Insulinoma-Associated 1 (INSM1))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 17
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 17
    • 1
    克隆类型
    • 15
    • 3
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INSM1 antibody is un-conjugated
    应用范围
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to IA-1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    IA-1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human IA-1.
    亚型
    IgG
    Top Product
    Discover our top product INSM1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    INSM1 (Insulinoma-Associated 1 (INSM1))
    别名
    INSM1 / IA1 (INSM1 产品)
    别名
    IA-1 antibody, IA1 antibody, INSM-1 antibody, Insm1 antibody, fc13a09 antibody, wu:fc13a09 antibody, zINSM-1 antibody, zgc:63866 antibody, INSM1 antibody, ia-1 antibody, zgc:77257 antibody, INSM transcriptional repressor 1 antibody, insulinoma-associated 1 antibody, insulinoma-associated 1b antibody, insulinoma associated 1 antibody, insulinoma associated 1 L homeolog antibody, insulinoma-associated 1a antibody, INSM1 antibody, Insm1 antibody, insm1b antibody, insm1 antibody, insm1.L antibody, insm1a antibody
    背景
    IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100 % of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.Synonyms: Insulinoma-associated protein 1, Zinc finger protein IA-1
    基因ID
    3642
    NCBI登录号
    NP_002187
    UniProt
    Q01101
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