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HINT1 抗体 (Center)

This 兔 多克隆 antibody specifically detects HINT1 in WB, IF 和 EIA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN499948
发货至: 中国
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Quick Overview for HINT1 抗体 (Center) (ABIN499948)

抗原

See all HINT1 抗体
HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

适用

  • 64
  • 50
  • 34
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 60
  • 4

克隆类型

  • 49
  • 15
多克隆

标记

  • 30
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HINT1 antibody is un-conjugated

应用范围

  • 35
  • 22
  • 19
  • 17
  • 14
  • 14
  • 13
  • 8
  • 3
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    特异性

    This antibody reacts to HINT1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    HINT1 antibody was raised against a 17 amino acid peptide near the center of the human HINT1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

    别名

    HINT1

    背景

    Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.Synonyms: Adenosine 5'-monophosphoramidase, HINT, HINT1, Histidine triad nucleotide-binding protein 1, PKCI-1, PKCI1, PRKCNH1, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1

    基因ID

    3094

    NCBI登录号

    NP_005331

    UniProt

    P49773
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