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GSTP1 抗体 (Center)

This anti-GSTP1 antibody is a 兔 多克隆 antibody detecting GSTP1 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499938
发货至: 中国

Quick Overview for GSTP1 抗体 (Center) (ABIN499938)

抗原

See all GSTP1 抗体
GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This GSTP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Center

    特异性

    This antibody reacts to GSTP1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    GSTP1 antibody was raised against a 14 amino acid peptide from near the center of human GSTP1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

    别名

    GSTP1 / GST3

    背景

    Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism (i.e., the metabolism of environmental mutagens and carcinogens) and may play a role in susceptibility to cancer. More recent experiments have suggested that differential expression of GSTP1 also contributes to the sensitivity of xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders such as Parkinson's disease. CpG island hypermethylation of the GSTP1 promoter leading to the silencing of the GSTP1 gene has also been linked to cancer.Synonyms: FAEES3, GST class-pi, GST pi, GSTP1-1, Glutathione S-transferase P

    基因ID

    2950

    NCBI登录号

    NP_000843

    UniProt

    P09211

    途径

    Cellular Response to Molecule of Bacterial Origin
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