GLE1 抗体 (C-Term)
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Quick Overview for GLE1 抗体 (C-Term) (ABIN499892)
抗原
See all GLE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to GLE1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Gle1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Gle1.
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亚型
- IgG
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anti-GLE1 RNA Export Mediator (GLE1) (AA 141-380) antibody
GLE1 适用: 人 ELISA, WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 140-240) antibodyGLE1 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 1-698) antibodyGLE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 611-698) antibodyGLE1 适用: 大鼠 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 218-267) antibodyGLE1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GLE1 (GLE1 RNA Export Mediator (GLE1))
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别名
- GLE1 / GLE1L
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背景
- The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.Synonyms: GLE1-like protein, Nucleoporin GLE1
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基因ID
- 2733
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NCBI登录号
- NP_001003722
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UniProt
- Q53GS7
抗原
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