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GLE1 抗体 (C-Term)

This anti-GLE1 antibody is a 兔 多克隆 antibody detecting GLE1 in WB, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN499892
发货至: 中国

Quick Overview for GLE1 抗体 (C-Term) (ABIN499892)

抗原

See all GLE1 抗体
GLE1 (GLE1 RNA Export Mediator (GLE1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GLE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to GLE1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Gle1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Gle1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    GLE1 (GLE1 RNA Export Mediator (GLE1))

    别名

    GLE1 / GLE1L

    背景

    The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.Synonyms: GLE1-like protein, Nucleoporin GLE1

    基因ID

    2733

    NCBI登录号

    NP_001003722

    UniProt

    Q53GS7
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