GFRA2 抗体 (Middle Region)
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北京 101111
Quick Overview for GFRA2 抗体 (Middle Region) (ABIN499885)
抗原
See all GFRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- GFR alpha 2 antibody was raised against a peptide corresponding to amino acids 377 to 391 of human GFR alpha 2.
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纯化方法
- DEAE
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免疫原
- Human GFR alpha 2 Peptide
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亚型
- IgG
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anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 301-360) antibody
GFRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) antibodyGFRA2 适用: 人 WB, ELISA, IF 宿主: 小鸡 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 242-415) antibodyGFRA2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) antibodyGFRA2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (C-Term) antibodyGFRA2 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 360-464) antibodyGFRA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (C-Term) antibodyGFRA2 适用: 人, 小鼠, 大鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 362-411) antibodyGFRA2 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 377-391) antibodyGFRA2 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) antibodyGFRA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1/1000 to 1/2000. A 52 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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别名
- GFRA2 / GDNFR-beta
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背景
- Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRbeta, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently. GFRalpha-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRalpha-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.Synonyms: GDNF family receptor alpha-2, GDNF receptor beta, GDNFRB, GFR-alpha-2, Neurturin receptor alpha, RET ligand 2, RETL2, TGF-beta-related neurotrophic factor receptor 2, TRNR2
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基因ID
- 2675
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UniProt
- O00451
抗原
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