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GFRA2 抗体 (Middle Region)

This anti-GFRA2 antibody is a 兔 多克隆 antibody detecting GFRA2 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499885
发货至: 中国

Quick Overview for GFRA2 抗体 (Middle Region) (ABIN499885)

抗原

See all GFRA2 抗体
GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

适用

  • 55
  • 33
  • 22
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 54
  • 2
  • 1
  • 1

克隆类型

  • 56
  • 1
多克隆

标记

  • 29
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This GFRA2 antibody is un-conjugated

应用范围

  • 48
  • 21
  • 13
  • 13
  • 10
  • 8
  • 6
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    特异性

    GFR alpha 2 antibody was raised against a peptide corresponding to amino acids 377 to 391 of human GFR alpha 2.

    纯化方法

    DEAE

    免疫原

    Human GFR alpha 2 Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1/1000 to 1/2000. A 52 kDa band should be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

    别名

    GFRA2 / GDNFR-beta

    背景

    Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRbeta, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently. GFRalpha-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRalpha-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.Synonyms: GDNF family receptor alpha-2, GDNF receptor beta, GDNFRB, GFR-alpha-2, Neurturin receptor alpha, RET ligand 2, RETL2, TGF-beta-related neurotrophic factor receptor 2, TRNR2

    基因ID

    2675

    UniProt

    O00451
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