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GFRA1 抗体 (Intermediate Domain)

This anti-GFRA1 antibody is a 兔 多克隆 antibody detecting GFRA1 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499883
发货至: 中国

Quick Overview for GFRA1 抗体 (Intermediate Domain) (ABIN499883)

抗原

See all GFRA1 抗体
GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

适用

  • 64
  • 37
  • 18
  • 16
人, 小鼠, 大鼠

宿主

  • 60
  • 7
  • 2

克隆类型

  • 62
  • 7
多克隆

标记

  • 33
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GFRA1 antibody is un-conjugated

应用范围

  • 48
  • 20
  • 17
  • 15
  • 13
  • 13
  • 10
  • 8
  • 8
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intermediate Domain

    特异性

    GFR alpha 1 antibody was raised against a peptide corresponding to amino acids 369 to 382 of human GFR alpha 1.

    纯化方法

    DEAE Chromatography

    免疫原

    Human GFR alpha 1 (Intermediate Domain) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

    别名

    GFRA1 / GDNFR-alpha

    背景

    Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently. GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRalpha-1 recently. GFRalpha-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRalpha and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.Synonyms: GDNF family receptor alpha-1, GDNF receptor alpha, GDNFRA, GFR-alpha-1, RET ligand 1, RETL1, TGF-beta-related neurotrophic factor receptor 1, TRNR1

    基因ID

    2674

    UniProt

    P56159
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