FKBP15 抗体 (N-Term)
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Quick Overview for FKBP15 抗体 (N-Term) (ABIN499840)
抗原
See all FKBP15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to FKBP15.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- FKBP15 antibody was raised against a 15 amino acid peptide from near the amino terminus of human FKBP15.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))
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别名
- FKBP15
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背景
- FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.Synonyms: 133 kDa FK506-binding protein, FK506-binding protein 15, FKBP133, KIAA0674, WAFL, WASP and FKBP-like
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基因ID
- 23307
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NCBI登录号
- NP_056073
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UniProt
- Q5T1M5
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途径
- SARS-CoV-2 Protein Interactome
抗原
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