FAF1 抗体 (C-Term)
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北京 101111
Quick Overview for FAF1 抗体 (C-Term) (ABIN499818)
抗原
See all FAF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to FAF1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- FAF1 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FAF1.
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亚型
- IgG
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anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibody
FAF1 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal CPTC-FAF1-2 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibodyKD Validated FAF1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB8245 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 551-650) antibodyFAF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-650) antibodyFAF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-650) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 551-650) antibodyFAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 490-629) antibodyFAF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (C-Term) antibodyFAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-280) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
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别名
- FAF1
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背景
- Fas-associated protein 1 (FAF1) was initially identified as a Fas-binding pro-apoptotic protein that is component of the death-inducing signaling complex in Fas-mediated apoptosis (1). FAF1 can also induce apoptosis in the absence of extrinsic death signals when overexpressed although it does not contain typical death motifs such as the death domain, death effector domain, and caspase recruitment domain (1,2). Overexpression of FAF1 also decreases the basal level of NF-kappaB activity in transfected 293 cells, inhibits NF-kappaB activity induced by TNF-alpha, IL-1beta and lipopolysaccharide, and prevents NF-kappaB translocation to the nucleus (3), suggesting that another role of FAF1 is to negatively regulate the activity of NF-kappaB. FAF1 can also interact with the inflammatory signaling PYRIN-containing Apaf-1-like proteins (PYPAFs, also called NALPs) such as PYPAF1, PYPAF2 (NALP2), and PYPAF7, suggesting FAF1 may also be involved in the inflammation pathway (4). Multiple differentially spliced isoforms of FAF1 are known to exist.Synonyms: CGI-03, FAS-associated factor 1, UBX domain-containing protein 12, UBX domain-containing protein 3A, UBXD12, UBXN3A
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基因ID
- 11124
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NCBI登录号
- NP_008982
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UniProt
- Q9UNN5
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途径
- Maintenance of Protein Location
抗原
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