ECSIT 抗体 (C-Term)
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Quick Overview for ECSIT 抗体 (C-Term) (ABIN499780)
抗原
See all ECSIT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT.
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纯化方法
- Ion exchange chromatography
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免疫原
- Human ECSIT (C-Terminus) Peptide
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亚型
- IgG
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anti-ECSIT (ECSIT) (AA 185-431) antibody
ECSIT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (AA 20-431) antibodyECSIT 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-ECSIT (ECSIT) (AA 241-290) antibodyECSIT 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (AA 51-100) antibodyECSIT 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (Middle Region) antibodyECSIT 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) antibodyECSIT 适用: 人 WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ECSIT
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别名
- ECSIT
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背景
- Activation of NF-?B as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses (reviewed in 1). Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 (2) to kinases such as IRAK (3) and other intermediates such as TNF receptor associated factor (TRAF)-6 (4). ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway (5). Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis (6), indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.Synonyms: ECSIT homolog (Drosophila), Evolutionarily conserved signaling intermediate in Toll pathway, SITPEC, Signaling intermediate in toll pathway evolutionarily conserved, mitochondrial
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基因ID
- 51295
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NCBI登录号
- NP_057665
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UniProt
- Q9BQ95
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途径
- TLR signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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