DISP2 抗体 (C-Term)
This anti-DISP2 antibody is a 兔 多克隆 antibody detecting DISP2 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for DISP2 抗体 (C-Term) (ABIN499750)
抗原
See all DISP2 抗体
DISP2
(Dispatched Homolog 2 (DISP2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This DISP2 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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特异性
- This antibody reacts to Disp2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Disp2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human Disp2.
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亚型
- IgG
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anti-Dispatched Homolog 2 (DISP2) (AA 1101-1200) antibody
DISP2 适用: 人 IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: Disp2 antibody can be used for the detection of Disp2 by Western blot at 1 -2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- DISP2 (Dispatched Homolog 2 (DISP2))
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别名
- DISP2 / DISPB
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背景
- Disp2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the Disp proteins have been implicated in these pathways. Recently, it has been shown that Disp2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased Disp2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by Disp2 mutants. At least two isoforms of Disp2 are known to exist. This Disp2 antibody is predicted to not cross-react with Disp1 or Disp3.Synonyms: KIAA1742, Protein dispatched homolog 2
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基因ID
- 85455
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UniProt
- A7MBM2
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途径
- Hedgehog Signaling
抗原
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