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DISC1 抗体 (Center)

DISC1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499748
发货至: 中国
  • 抗原 See all DISC1 抗体
    DISC1 (Disrupted in Schizophrenia 1 (DISC1))
    抗原表位
    • 15
    • 14
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 70
    • 24
    • 14
    • 1
    人, 小鼠
    宿主
    • 69
    • 4
    • 1
    • 1
    克隆类型
    • 71
    • 6
    多克隆
    标记
    • 42
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DISC1 antibody is un-conjugated
    应用范围
    • 47
    • 31
    • 26
    • 14
    • 14
    • 11
    • 11
    • 7
    • 6
    • 5
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to DISC1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    DISC1 antibody was raised against a 18 amino acid peptide from near the center of human DISC1.
    亚型
    IgG
    Top Product
    Discover our top product DISC1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    DISC1 (Disrupted in Schizophrenia 1 (DISC1))
    别名
    DISC1 (DISC1 产品)
    别名
    DISC1 antibody, C1orf136 antibody, SCZD9 antibody, disrupted in schizophrenia 1 antibody, disrupted in schizophrenia 1 protein antibody, disc1 antibody, DISC1 antibody, LOC100580606 antibody, Disc1 antibody
    背景
    Disrupted in schizophrenia 1 (DISC1) is a candidate gene for susceptibility to schizophrenia. It was discovered through chromosomal analysis of a large Scottish family whose members exhibited schizophrenia and related psychiatric disorders. Through yeast two-hybrid screening, it was discovered that DISC1 interacts with many members of the centrosome and cytoskeletal system including MAP1A and Nudel. More recently, DISC1 has been found to regulate the transport of a complex containing Nudel, the lissencephaly-1 (LIS1) protein, and 14-3-3e from neuronal cell bodies to the axons by the action of the microtubule-dependent directed motor protein kinesin-1, also known as KIF5A. Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation. DISC1 has at least four known isoforms.Synonyms: DISC-1, Disrupted in schizophrenia 1 protein, KIAA0457
    基因ID
    27185
    NCBI登录号
    NP_061132
    UniProt
    Q9NRI5
    途径
    Regulation of Cell Size
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