DISC1 抗体 (Middle Region)
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北京 101111
Quick Overview for DISC1 抗体 (Middle Region) (ABIN5518699)
抗原
See all DISC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-DISC1 Antibody
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序列
- EKQQLQKEIE ALQARMF
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by two amino acids,and from the related rat sequence by four amino acids.
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产品特性
- Anti-DISC1 Antibody-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human DISC1, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.
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亚型
- IgG
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anti-Disrupted in Schizophrenia 1 (DISC1) (AA 102-261) antibody
DISC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) antibodyDISC1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 1-200) antibodyDISC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (C-Term) antibodyDISC1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (C-Term) antibodyDISC1 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 99-325) antibodyDISC1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 101-200) antibodyDISC1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 761-832) antibodyDISC1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (Internal Region) antibodyVerified DISC1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 701-728), (C-Term) antibodyDISC1 适用: 人 WB 宿主: 小鼠 Monoclonal 584CT4-2-1 unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
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别名
- DISC1
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背景
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Background: DISC1 (Disrupted in Schizophrenia 1), is a protein that is encoded by the DISC1 gene in humans. Ma et al. (2002) determined that the mouse Disc1 gene maps to chromosome 8 in a region with homology of synteny to human chromosome 1q42. Ozeki et al. (2003) demonstrated that rodent Disc1 expression displayed pronounced developmental regulation, with the highest levels in late embryonic life during development of the cerebral cortex. Millar et al. (2005) showed that DISC1 interacts with the UCR2 domain of phosphodiesterase-4B, implicated in susceptibility to schizophrenia, and that elevation of cellular cAMP leads to dissociation of PDE4B from DISC1 and in increase in PDE4B activity.
Gene Full Name: DISC1 scaffold protein
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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分子量
- 94 kDa
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基因ID
- 27185
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UniProt
- Q9NRI5
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途径
- Regulation of Cell Size
抗原
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