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ATF6 抗体 (AA 431-530)

This anti-ATF6 antibody is a 兔 多克隆 antibody detecting ATF6 in WB, ELISA, IF (p), IF (cc), IHC (p), ICC 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN4996973
发货至: 中国

Quick Overview for ATF6 抗体 (AA 431-530) (ABIN4996973)

抗原

See all ATF6 抗体
ATF6 (Activating Transcription Factor 6 (ATF6))

适用

  • 94
  • 43
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  • 1
  • 1
人, 大鼠

宿主

  • 88
  • 10
  • 1

克隆类型

  • 88
  • 11
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
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This ATF6 antibody is un-conjugated

应用范围

  • 84
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  • 3
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Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 16
    • 14
    • 13
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    • 6
    • 4
    • 3
    • 2
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    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 431-530

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ATF6

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ATF6 (Activating Transcription Factor 6 (ATF6))

    别名

    ATF6

    背景

    Synonyms: Cyclic AMP-dependent transcription factor ATF-6 alpha, ATF6-alpha, ATF6

    Background: Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.

    基因ID

    22926

    UniProt

    P18850

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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