CIDEB 抗体 (C-Term)
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Quick Overview for CIDEB 抗体 (C-Term) (ABIN499629)
抗原
See all CIDEB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- CIDE-B antibody was raised against a peptide corresponding to amino acids 204 to 219 of murine CIDE-B. It has no cross activity to CIDE-A.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Mouse mCIDE-B (C-Terminus) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CIDE-B antibody can be used for detection of CIDE-B at 1/500 to 1/1000dilution. An approximately 25 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))
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别名
- CIDE-B
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背景
- Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (1).CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow (1).Synonyms: CIDE B, CIDEB, Cell Death Activator CIDE-B, Cell Death-Inducing DFFA-Like Effector B
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基因ID
- 12684
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UniProt
- O70303
抗原
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